**The cyclodextrins have a huge range of applications in varied areas of drug delivery and pharmaceutical industry because of their characteristic ability of complexation and other versatile characteristics.
** Cyclodextrins possess the ability to form inclusion Complexes with varied drug molecules by taking up a drug molecule in their cavity.
** The factors favouring complex formation are release of enthalpy rich water molecules from the cavity and other non-covalent interactions like electrostatic interactions, Van der Waal's interactions, hydrophobic interactions, hydrogen bonding, release of conformational strain and charge transfer interactions.
** Methods to monitor the physicochemical changes (like changes in conductance or pH etc.) occurring after the formation of inclusion complexes are applied to study the mentioned changes of the aqueous complexation media.
** We have thoroughly discussed how to increase the efficiency of formation of complexes.
** Non-conventional cyclodextrin complexes gain more importance in the aspects of drug solubilisation by means of molecular aggregation.
ORGANIC CHEMISTRY- I (NATURE OF BONDING AND STEREOCHEMISTRY)- CYCLODEXTRINS – 2